KMID : 0358820080350060755
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Journal of Korean Society of Plastic and Reconstructive Surgeons 2008 Volume.35 No. 6 p.755 ~ p.758
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New Measurement Method of Wound Healing by Stereoimage Optical Topometer System
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Han Seung-Kyu Kim Woo-Kyung
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Abstract
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Purpose: In order to determine the amount of wound healing, objective sequential assessments of changes in wound size and depth are essential. Although a variety of measurements for wound healing have been proposed, a gold standard for quantifying day-to-day changes in healing has not been established. We present here a simple and non-invasive wound measurement method that quantitatively and accurately documents changes of the size of a raw surface and the volume of a soft tissue defect using a stereoimage optical topometer(SOT) system.
Methods: Using a 5mm diameter biopsy punch, four circular wounds were created on abdominal area of a diabetic mouse. Photographs were taken using SOT system at baseline, 5th day and 10th postoperative day. The wound margin was traced on a digitalized photo and evaluated the area and the volume of the wound by SOT system.
Results: The SOT system calculated a mean wound surface of 15.93+/-0.29mm2 and volume of 827.50+/-88.86 intensity/pixel x area(I/PA) immediately after wounding. On the 5th day after the operation wound surface declined by 10.73mm2 and on the 10th day declined by 5.95mm2. The wound volume also declined from 827.50 I/PA to 161.75 I/PA and 30.50 I/PA on 0, 5th and 10th day, respectively.
Conclusion: The SOT system described in this study represents a reliable, simple, practical, and non-invasive technique to accurately monitor and evaluate wound healing.
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KEYWORD
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Wound healing, Stereoimage optical topometer
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